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Do You Have The "BOSS" Gene?



In the world of genetics, the COMT gene stands out for its profound impact on both mental and physical health. Known scientifically as Catechol-O-Methyltransferase, the COMT gene is involved in the breakdown of dopamine, a key neurotransmitter that influences mood, motivation, and cognitive function. When there is a mutation in this gene, it can lead to significant changes in personality and health.


Characteristics of a Person with a COMT Gene Mutation


Overthinking and Anxiety

One of the most notable characteristics of individuals with a COMT gene mutation is their tendency to overthink. These individuals often have a heightened state of mental activity, leading to an overactive mind that can make it difficult to relax. This can contribute to anxiety, as the constant stream of thoughts can be overwhelming and challenging to manage.


Entrepreneurial Mindset and Goals

Interestingly, the same mutation that causes overthinking and anxiety can also foster an entrepreneurial mindset. The ability to think deeply and critically can drive innovative thinking and a desire to achieve ambitious goals. Many people with this mutation are highly motivated and have a strong drive to succeed, often leading them to pursue entrepreneurial ventures, hence the meaning behind its cleverly crafted nick-name.


Hormonal Imbalances

Beyond mental characteristics, the COMT gene mutation can also affect physical health, particularly in terms of hormone metabolism. This gene plays a role in the clearance of oestrogen from the liver. Poor oestrogen clearance can lead to hormonal imbalances in both men and women, contributing to issues such as PMS, oestrogen dominance, PCOS, gynecomastia in men, and increased risks of certain cancers, especially in women.


Extra Nutritional Requirements for COMT Mutation Carriers


If you have a COMT gene mutation, your body may have specific nutritional needs to support optimal health. Here are some key nutrients to consider:


Magnesium

Magnesium is crucial for many biochemical reactions in the body, including those that involve the nervous system. It can help reduce anxiety and promote relaxation, making it particularly beneficial for individuals with a COMT mutation.


Vitamin B12

Vitamin B12 is essential for brain health and energy production. For those with a COMT mutation, specific forms of vitamin B12 such as adenosylcobalamin or hydroxocobalamin are often more effective. These forms are more easily utilised by the body and can help support cognitive function and overall well-being.


Understanding Your Genetics


If you suspect that you might have a mutation in your COMT gene, understanding your genetic makeup can be a valuable step toward optimising your health. By knowing more about your genes, you can tailor your diet, lifestyle, and supplement choices to better meet your unique needs.



The COMT gene mutation, or what we might call the "BOSS gene," can significantly influence your mental and physical health. From fostering an entrepreneurial mindset to contributing to anxiety and hormonal imbalances, this genetic variation presents both challenges and opportunities. If you're interested in learning more about your genetics and how they might be influencing your health, I invite you to contact me. Together, we can explore your genetic profile and develop a personalised plan to help you thrive.


Reach out today to discover if you have the "BOSS gene" and start your journey toward a healthier, more balanced life.



In health and love

Deena

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